Image 001 Image 002
Partners Healthcare Systems
Follow us:User Survey - click here for more informationUser Survey - click here for more information
Human immunodeficiency virus (HIV-1 and HIV-2)

Human immunodeficiency virus. A non-taxonomic and historical term referring to any of two species, specifically HIV-1 and/or HIV-2. Prior to 1986, this was called human T-lymphotropic virus type III/lymphadenopathy-associated virus (HTLV-III/LAV). From 1986-1990, it was an official species called HIV. Since 1991, HIV was no longer considered an official species name; the two species were designated HIV-1 and HIV-2.
(Source: National Library of Medicine 2013 MeSH Scope Note and Classification)


In Figures 1, 2 and 3, a thin slice from a montaged tomographic reconstruction of a region of a crypt of Lieberkühn in HIV-1 infected humanized Bone Marrow Liver Thymic (BLT) mouse colon is shown. In Figures 1 and 2, the virions themselves have been modeled in position (the envelopes as blue spheres, the bullet-shaped cores in magenta and presumptive surface spikes as tiny yellow spheres) and the tomographic slice superimposed beneath them. This view allows for the virions in the intercellular spaces between cells to be visualized relative to the surrounding tissue components.

The images shown were provided by Mark S. Ladinsky and Pamela J. Bjorkman, PhD, of the California Institute of Technology, Pasadena, CA and Douglas Kwon, MD PhD, of the Ragon Institute of MGH, MIT and Harvard and Harvard University, Cambridge, MA.

Related Cases
View Case #22001
A male in his twenties with worsening mental status and progressive abdominal pain, nausea, headache, myalgias, fever and facial rash
View Case
View Case #21004
A patient with advanced AIDS with cavitary lung lesion, generalized lymphadenopathy, and pericardial effusion
View Case
View Case #20001
A man with HIV presenting with skin lesions after initiating antiretroviral therapy (ART)
View Case
View Case #19011
A Progressive Ulcerating Facial Lesion in a Ugandan Man with HIV
View Case
View Case #18002
Abdominal cramps and diarrhea in an HIV-infected man who has sex with men
View Case

Show All Related Cases (137) »

Related Images From Cases

Show All Related Images (377) »

  1. National Library of Medicine 2013 MeSH Scope Note and Classification

National Library of Medicine MeSH Classification

RNA Viruses
Lentiviruses, Primate
Simian immunodeficiency virus